In a mixing bowl, add cubed pieces of chicken, flour, black pepper, Creole seasoning, and garlic powder. Combine making sure that the chicken pieces are well coated. In another small bowl, combine the Worcestershire sauce and lemon juice together, and set aside.
In a large skillet, over medium-heat, melt the butter. Add the seasoned chicken and pan-fry until chicken is browned. Carefully pour in the Worcestershire and lemon juice mixture into the skillet. Bring the sauce to a boil then lower heat to Medium-Low and continue to cook until chicken is completely cooked through.